Supercard DSTwo released the update patch for 3DS V2.2.0-4
If you dont know the 3DS firmware V2.2.0-4, please take a look here: 3DS new firmware V2.2.0-4 has released, r4i gold card can work on it
[2011-11-07]DSTWO Fireware v1.13 released!
DSTWO Fireware v1.13
Fixed for 3DS ver2.2.0-4J, Now you can feel free to enjoy Mario 3DS orignal cart on your 3DS.
Important: Please make sure the power is enough! And don't do anything unnecessary!
How to use:
copy the dstwoupdate.dat file to the root of microsd card, then upgrade it.
We suggest you to upgrade it on a DS console or never upgraded console.
You can update it from here: http://down.supercard.sc/download/ds..._v1.13_eng.zip
Congratulations to DStwo team, until now, R4i gold and DStwo team have already released the news that their cards can support the new 3DS firmware..there will be more and more cards will reelase the update firmware, just focused on it.
Source: DSTwo forum