I switched on my ps3 today to find that fw 2.50 is now live. I downloaded and installed it to find that all BD-J homebrew for PS3 no longer works. You get an error code saying it can't be played. And yes it was set up right and was fully working on my previous firmware 2.43.
Oh well it was fun having homebrew on ps3 whilst it lasted.
You might be able to bypass this update using PS3Proxy but I'm not sure.